Dr. Rachna Shroff, Renowned Cancer Researcher, Dies at 47

Dr. Rachna Shroff, an esteemed Indian-American oncologist and cancer researcher who dedicated her professional career to fighting the very disease that ultimately claimed her life, has passed away at the age of 47. Her death was announced by the American Society of Clinical Oncology (ASCO) and the University of Arizona, where she held key academic, clinical, and leadership roles.

Dr. Shroff specialized in gastrointestinal, pancreatic, and hepatobiliary cancers, focusing much of her life’s work on understudied and underfunded conditions such as bile duct cancer, gallbladder cancer, and liver cancers. She was diagnosed earlier with terminal adenocarcinoma, a form of cancer starting in the glands lining internal organs, which had already spread after initially presenting as a swollen lymph node.

A Pioneering Legacy in Oncology

Throughout her distinguished career, Dr. Shroff established herself as an internationally respected clinician-scientist, authoring more than 80 scientific publications and delivering over 130 professional presentations. Colleagues frequently remembered her not only for her relentless scientific rigor and clinical trial leadership—such as her work advancing therapies for biliary tract cancers—but also for her humility, warmth, and signature personal style.

Leaders from the American Society of Clinical Oncology recalled her deep commitment to clinical research and her ability to build collaborative communities among oncologists. Her professional contributions extended to mentoring early-stage investigators, a mission she prioritized deeply throughout her tenure.

Lasting Impact and Mentorship

Facing her advanced health diagnosis, Dr. Shroff focused heavily on ensuring her life’s passions would endure beyond her lifetime. She successfully established the Conquer Cancer Rachna Shroff Young Investigator Award in Biliary Cancers to support and mentor early-stage researchers entering the field.

She is survived by her husband, Dr. Puneet Shroff, a physician and professor of medicine, their two children, Simran and Sachin, as well as her parents and sister. Institutional leaders, colleagues, and trainees worldwide have continued to share tributes celebrating her resilience, innovation, and the profound impact she left on the global oncology community.